Program

Timetable

Short Course/Annual Meeting Joint Distinguished Lecture

October 20 (Mon.) 17:30-18:30 Room A (1F Exhibition Hall A)

ChairToshiya Katsura
School of Pharmacy, Ritsumeikan University

Dynamics of the Function and Regulation of the Endoplasmic Reticulum

Distinguished Professor Kazutoshi Mori
Institute for Advanced Study, Kyoto University

https://kuias.kyoto-u.ac.jp/e/profile/kmori/
https://www.upr.biophys.kyoto-u.ac.jp/en/

Special Invited lecture 1

October 21 (Tue.) 13:00-14:00 Room A (1F Exhibition Hall A)

ChairYasuhisa Nagasaka
Early Development & Translational Science, Astellas Pharma Inc.

Charting Chemical-Microbiome Interaction Landscape

Professor Kiran Patil
MRC Toxicology Unit, University of Cambridge

https://www.mrc-tox.cam.ac.uk/staff/kiran-patil

Special Invited lecture 2

October 23 (Thu.) 11:15-12:15 Room A (1F Exhibition Hall A)

ChairHiroshi Yamazaki
Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University

Adventures in CYP2 and CYP4 Biochemistry

Professor Allan Rettie
School of Pharmacy, University of Washington

https://sop.washington.edu/people/allan-rettie/

President's Lecture

October 20 (Mon.) 18:30-18:50 Room A (1F 2nd Exhibition Hall A)

ChairFumiyoshi Yamashita
Graduate School of Pharmaceutical Sciences, Kyoto University

Message from the president (Tentative)

SpeakerYukio Kato
Department of Pharmaceutical Sciences, Kanazawa University

New President's Lecture

October 22 (Wed.) 11:30-11:50 Room A (1F 2nd Exhibition Hall A)

ChairYukio Kato
Department of Pharmaceutical Sciences, Kanazawa University

Message from the new president (Tentative)

SpeakerHiroyuki Kusuhara
Graduate School of Pharmaceutical Sciences, The University of Tokyo

Selected Talk

October 21 (Tue.) 12:05-12:45 Room B (1F 2nd Exhibition Hall D)

SpeakerHiroyuki Kusuhara
Graduate School of Pharmaceutical Sciences, The University of Tokyo

Special Session

October 22 (Wed.) 13:10-15:40 Room A (1F 2nd Exhibition Hall A)

The Near Future of an AI Society: Harmonizing Intelligence and Mind

ChairFumiyoshi Yamashita
Graduate School of Pharmaceutical Sciences, Kyoto University
ChairTomohiro Terada
Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital
SS-1Augmenting Human Intelligence with AI: Potentials and Challenges of Large Language Models
SpeakerYuichi Inoue
Sakana AI
SS-2The Evolutionary Origins and Future of the Artistic Mind
SpeakerAya Saito
Institute for Philosophy and Science of Art, Kyoto University of the Arts
SS-3
SpeakerTBD
SS-4AI That Reads the Room: Understanding, Generating, and Transforming Nonverbal Behaviors
SpeakerKoji Inoue
Graduate School of Informatics, Kyoto University
Panel Discussion

Organizering Committee Symposium

October 23 (Thu.) 8:30-11:00 Room A (1F 2nd Exhibition Hall A)

DMPK special issue: Future direction of animal alternative/microphysiological systems in drug discovery and development

ChairKazuo Takayama
Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo
ChairHiroshi Arakawa
Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
OCS-1Opportunities for microphysiological systems from the view of Japanese industries
SpeakerHitoshi Naraoka
Astellas Pharma Inc./ CSAHi-MPS
OCS-2Organoid guided Precision Pharmacology
SpeakerTakanori Takebe
Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), and Division of Stem Cell and Organoid Medicine, Osaka University
OCS-3Uncovering the mechanisms of the intractable lung diseases using iPS cells
SpeakerShimpei Gotoh
Center for iPS Cell Research and Application (CiRA), Kyoto University
OCS-4Microphysiological systems for pharmaceutical research of intestinal infectious diseases
SpeakerSayaka Deguchi
Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo
OCS-5Development and Application of Cardiac Organoids/Tissues from Human iPSCs
SpeakerShugo Tohyama
Fujita Medical Innovation Center Tokyo, Fujita Health University
OCS-6Development of iPS cell-derived intestinal cells as an in vitro model in drug discovery
SpeakerTakahiro Iwao
Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University

Symposium 1 (Metabolism and Toxicity DIS 2)

October 21 (Tue.) 9:30-11:30 Room A (1F 2nd Exhibition Hall A)

Current challenges and future perspective of drug metabolism research

ChairKouichi Yoshinari
Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
ChairYuu Miyauchi
Laboratory of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Sojo University
SY1-1Paradigm Shift in Drug Metabolism Research
SpeakerMiki Nakajima
Faculty of Pharmaceutical Sciences, Kanazawa University
SY1-2Pharmacogenomics Research: Current Landscape, Challenges, and Future Horizons
SpeakerMasahiro Hiratsuka
Laboratory of Pharmacogenomics, Graduate School of Pharmaceutical Sciences Tohoku University
SY1-3Current Status of Drug Metabolism Research in Clinical Practice and Prospects for Healthcare in 2040
SpeakerYoshimichi Sai
Kanazawa University Hospital
SY1-4Back to the basics: The interest of drug metabolism research in drug development for small molecules
SpeakerHideki Hirabayashi
Nagoya City University/ T.N.Technos Co., Ltd.
Panel Discussion

Symposium 2 (DDS DIS)

October 21 (Tue.) 9:30-11:30 Room B (1F 2nd Exhibition Hall D)

Beyond small molecules: DDS for new modalities

ChairKen-ichi Ogawara
Laboratory of Pharmaceutics, Kobe Pharmaceutical University
ChairTakanori Kanazawa
Graduate School of Biomedical Sciences, Tokushima University
SY2-1Living cell-based drug delivery systems for tumor targeting
SpeakerYusuke Kono
Kobe Pharmaceutical University
SY2-2Improved delivery of liposomal anticancer drugs to refractory tumors by Salmonella administration
SpeakerShoko Nomura
Graduate School of Biomedical Science, Nagasaki University
SY2-3Tumorous pH-responsive polyzwitterion for tumor delivery of nucleic acid drugs
SpeakerHiroyasu Takemoto
Graduate School of Medicine, Kyoto Prefectural University of Medicine
SY2-4Current status of drug delivery application of extracellular vesicles
SpeakerMasaharu Somiya
SANKEN, Osaka University
SY2-5Cyclic Peptides for Drug Development: Pharmacokinetics and Drug Delivery Systems
SpeakerAyahisa Watanabe
Laboratory for Medicinal Chemistry Research, Pharmaceutical Research Division, Shionogi & Co., Ltd

Symposium 3 (Transporter DIS)

October 21 (Tue.) 9:30-11:30 Room C (B1F 1st Exhibition Hall A)

Frontiers in Transporter Research

ChairKatsuhisa Inoue
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
ChairShin-ichi Akanuma
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
SY3-1Regulation of transporter expression by cardiac glycosides and its application to cancer therapy
SpeakerTakuto Fujii
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
SY3-2Elucidation of the physiological significance of BCRP and its role in drug pharmacokinetics
SpeakerYusuke Masuo
Faculty of Pharmaceutical Sciences, Kanazawa University
SY3-3Functional identification of the SLC49A family as novel organic cation transporters
SpeakerTomoya Yasujima
Graduate School of Pharmaceutical Sciences, Nagoya City University
SY3-4Integrated approach of molecular simulation and AlphaFold reveals molecular structure and function of transporters
SpeakerKei-ichi Okazaki
Research Center for Computational Science, National Institutes of Natural Sciences

Symposium 4 (Absorption DIS)

October 21 (Tue.) 14:15-16:45 Room A (1F 2nd Exhibition Hall A)

DRUG ABSORPTION FROM ZERO: The New World of Drug Absorption and Disposition Innovated by Cutting-Edge Technology

ChairYoshiyuki Shirasaka
Laboratory of Pharmaceutics, Showa Pharmaceutical University
ChairToshimichi Nakamura
Non-Clinical Biomedical Science, Astellas Pharma Inc.
SY4-1Pharmaceutical Perspective: Quantitative analysis of oral drug absorption using Gastrointestinal imaging with quantum dot and tissue-clearing technology
SpeakerYoshiyuki Shirasaka
Laboratory of Pharmaceutics, Showa Pharmaceutical University
SY4-2Pharmacokinetic Perspective: Prediction of the properties of drug intestinal absorption with differentiated intestinal cells originated from human/animal crypts
SpeakerKazuya Maeda
Laboratory of Pharmaceutics, Kitasato University School of Pharmacy
SY4-3Clinical Pharmacometric Perspective: Artificial Intelligence (AI)-Based Model Analysis of Oral Absorption and Enterohepatic Circulation
SpeakerYasuhiro Tsuji
Laboratory of Clinical pharmacokinetics, School of Pharmacy, Nihon University
SY4-4Microbiological Perspective: Prevention and treatment for inflammatory bowel disease
SpeakerYuji Naito
Department of Human Immunology and Nutrition Science, Kyoto Prefctural University of Medicine
Panel Discussion

Symposium 5 (Efficacy and Safety DIS)

October 21 (Tue.) 14:15-16:45 Room B (1F 2nd Exhibition Hall D)

New pillars of cellular and vesicular kinetics and dynamics
Towards emergent evolution of CNS・Immunity・Cancer-targeting biopharmaceuticals

ChairMasanori Tachikawa
Graduate School of Biomedical Sciences, Tokushima University
ChairYuki Kishino
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY5-1Cell therapy and gene therapy products (tentative)
SpeakerTakeshi Hanada
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY5-2Exosomes research (tentative)
SpeakerWataru Obuchi
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY5-3Pharmacology, pharmacokinetics, and toxicology of LNP-mRNA products (tentative)
SpeakerShigetomo Tsujihata
FUJIFILM Corporation, Bio Science & Engineering Laboratory/FUJIFILM Toyama Chemical Co., Ltd.,
SY5-4Designer cells to engineer tissue environment
SpeakerSatoshi Toda
Institute for Protein Research, Osaka University
SY5-5Microglia implantation in the brain
SpeakerShuichi Koizumi
Faculty of Medicine, University of Yamanashi

Symposium 6 (AI/Machine Learning for Pharmacokinetic Prediction DIS)

October 22 (Wed.) 8:30-11:00 Room A (1F 2nd Exhibition Hall A)

Pioneering the Future: A Dialogue on AI/Machine Learning from Different Perspectives – The Intersection of Pharmacokinetics and Computational Science

ChairHideaki Mamada
Drug Metabolism and Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc.
SY6-1What does a machine learning researcher say?
SpeakerMasataka Kuroda
Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN)/Mitsubishi Tanabe Pharma Corporation
SY6-2Computational approaches for drug discovery through the integration of AI and simulation
SpeakerKei Terayama
Graduate School of Medical Life Science, Yokohama City University

ChairShinji Nakayama
DMPK Research Laboratories, Shoyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation
SY6-3Study of Recognition Capacity of Chemical Structures by Language AI
SpeakerTadahaya Mizuno
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo
SY6-4A Comparison of Machine Learning Approaches for Enhancing ADME Prediction Accuracy
SpeakerYohei Kosugi
Drug Metabolism, Pharmacokinetics & Modeling, Research, Takeda Pharmaceutical Company Limited

Panel Discussion
ChairHiroaki Iwata
Faculty of Medicine, Tottori University
ChairKoichi Handa
Discovery DMPK, Axcelead Tokyo West Partners Inc.

Symposium 7 (Dynamic education and cross-disciplinary DIS)

October 22 (Wed.) 8:30-11:00 Room B (1F 2nd Exhibition Hall D)

Basic course of pharmacokinetics on cross-disciplinary

ChairSeigo Sanoh
School of Pharmaceutical Sciences, Wakayama Medical University
ChairTakafumi Akabane
Translational & Biomedical Science, Early Development & Translational Science, Astellas Pharma Inc.
SY7-1MPS Basics and Beyond: How We Mimic & Use Biological Systems with Blood-Brain Barrier Model as an Example
SpeakerTomomi Furihata
Laboratory of Advanced Drug Development Sciences, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
SY7-2NAMs-based human pharmacokinetic prediction of food-related compounds (Tentative)
SpeakerTakashi Kitaguchi
Global Food Safety Institute, Nissin Foods Holdings Co., Ltd.
SY7-3From Basics to Breakthroughs: A Comprehensive Guide to Spatial Transcriptomics and Its Data Journey (Tentative)
SpeakerShinya Asano
Omics & Bioinformatics, DMPK Business Unit, Axcelead Drug Discovery Partners, Inc.
SY7-4Highlighting the Essentials of Pharmacokinetics of ADCs: An Overview, the Complexity of Bioanalysis, and Expectations for Pharmacokinetics Researchers (Tentative)
SpeakerYuki Kishino
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited

Symposium 8 (New modality DIS)

October 22 (Wed.) 8:30-11:00 Room C (B1F 1st Exhibition Hall A)

Frontiers of Brain-targeted Delivery for New Therapeutic Modalities: From Bench to Bedside

ChairSyunsuke Yamamoto
Drug Metabolism, Pharmacokinetics & Modeling, Research, Takeda Pharmaceutical Company Limited
ChairFuminori Sakurai
Faculty of Pharmacy, Kindai University
SY8-1Brain distribution of antibodies
SpeakerShinji Iwasaki
Drug Metabolism, Pharmacokinetics & Modeling, Research, Takeda Pharmaceutical Company Limited
SY8-2Novel Antibody Technology for Efficient Blood-Brain Barrier Transport and Sustained Retention in the Brain
SpeakerYuki Noguchi
Discovery Biologics Dept., Chugai Pharmaceutical Co., Ltd.
SY8-3Development of a small compound that transiently loosen the blood-brain barrier and facilitate drug delivery into the brain
SpeakerKeisuke Shirakura
Max Planck Institute for Molecular Biomedicine
SY8-4Intravenous administration of blood-brain barrier-permeable AAV vectors for cell type-specific gene expression in the brain
SpeakerHirokazu Hirai
Gunma University Graduate School of Medicine
SY8-5Convection-enhanced delivery
SpeakerRyuta Saito
Department of Neurosurgery, Graduate School of Medicine, Nagoya University

Symposium 9 (In vivo models DIS)

October 23 (Thu.) 8:30-11:00 Room B (1F 2nd Exhibition Hall D)

Advanced Humanized Animal Models in Drug Discovery: From Pharmacokinetics Prediction to Toxicity Evaluation and Precision Medicine

ChairTaiji Miyake
Pharmaceutical Science Dept., Chugai Pharmaceutical Co., Ltd.
ChairYuji Ishida
Department of Research and Development, PhoenixBio Co., Ltd.
SY9-1Quantitative prediction of drug–drug interactions using human liver chimeric mice
SpeakerTaiji Miyake
Pharmaceutical Science Dept., Chugai Pharmaceutical Co., Ltd.
SY9-2Development of a method for predicting human pharmacokinetics of low clearance compounds using chimeric mice with humanized livers
SpeakerKosuke Yoshida
DMPK Research Laboratories, Shoyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation
SY9-3Generation of humanized animal model using chromosome engineering technology and the application for drug discovery
SpeakerYasuhiro Kazuki
Chromosome Engineering Research Center, Tottori University, School of Life Science/ Faculty of Medicine, Tottori University
SY9-4PGx studies by using humanized mouse models
SpeakerKaoru Kobayashi
Meiji Pharmaceutical University
SY9-5Human PK prediction of Fc-fusion proteins using monkey and hFcRn Tg mice
SpeakerMiki Yokoyama
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY9-6Evaluation of fetal toxicity of thiopurine using Nudt15 R138C knock-In mice
SpeakerYoichi Kakuta
Division of Gastroenterology, Tohoku University Graduate School of Medicine

Symposium 10 (Analysis & Imaging DIS)

October 23 (Thu.) 9:00-11:00 Room C (B1F 1st Exhibition Hall A)

Advancing the Future of Pharmacokinetics and Safety Research with Imaging Technology

ChairYukari Tanaka
Drug Discovery Research Division, Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd.
ChairHidefumi Mukai
Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University
SY10-1Evaluation of drug delivery systems using in vivo confocal microscopy
SpeakerKazuko Toh
NucleoTIDE and PepTIDE Drug Discovery Center (TIDE), Institute of Integrated Research, Institute of Science Tokyo
SY10-2Species differences analysis of epyrifenacil-induced hepatotoxicity between mice and humans using mass spectrometry imaging in PXB mouse liver
SpeakerKohei Matsunaga
Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd.
SY10-3Novel light-sheet microscopy systems for 3D microanalysis of biological tissue specimens
SpeakerKohei Otomo
Biochemisty II, Faculty of Medicine, Juntendo University
SY10-4Evaluation Of Spatial Tissue Distribution of Novel Antibody Technology Enabling Efficient BBB Penetration And Long-Term Retention In The Brain (Tentative)
SpeakerKenta Haraya
Discovery Biologics Dept., Chugai Pharmaceutical Co., Ltd.
SY10-5Development of evaluation technology for drug efficacy using high-resolution X-ray CT imaging
SpeakerKohsuke Gonda
Department of Medical Physics, Graduate School of Medicine, Tohoku University

Symposium 11 (Modeling and Systems Pharmacology DIS)

October 23 (Thu.) 13:45-16:15 Room A (1F 2nd Exhibition Hall A)

Special Feature on Current State-of-the-Art Research in Systems Pharmacology

ChairSatoshi Nakayama
DMPK Research Laboratories, Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation
ChairYoshinobu Nakamaru
Clinical Pharmacology Strategy, Clinical Development, R&D Japan, Bristol-Myers Squibb K.K.
SY11-1Fast Virtual Patient Generation Using a Surrogate Model with Bayesian Optimization and Machine Learning (Tentative)
SpeakerHiroaki Iwata
Faculty of Medicine, Tottori University

ChairRyoko Sawamura
Quantitative Clinical Pharmacology Department, Daiichi Sankyo Company, Limited
ChairChie Emoto
Translational Research Division, Chugai Pharmaceutical Co., Ltd.
SY11-2Quantitative systems pharmacology model informs predictors for therapeutic effects on inflammatory responses in rheumatoid arthritis (Tentative)
SpeakerTomohisa Nakada
Discovery Technology Laboratories, Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation

ChairTsuyoshi Minematsu
Immuno-Oncology, Astellas Pharma Inc.
ChairShinichi Kijima
Pharmaceuticals and Medical Devices Agency
SY11-3Model-Informed Drug Development (MIDD) to Accelerate ADC Development and Maximize Therapeutic Index (Tentative)
SpeakerKimiko McGirr
QSP, Certara, Inc.

ChairHiroyuki Sayama
Translational & Biomedical Science, Early Development & Translational Science, Astellas Pharma Inc.
ChairYuki Iwaki
Clinical Pharmacology & Pharmacometrics, Global R&D, Janssen Pharmaceutical K.K.
SY11-4Physiologically-based quantitative translational modeling platform for designing bispecific T cell engagers (Tentative)
SpeakerTomoki Yoneyama
Takeda Pharmaceuticals International Co.

Panel Discussion
ChairTakashi Yoshikado
Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy
ChairTeruki Hamad
DMPK Business Unit, Axcelead Drug Discovery Partners, Inc.

Symposium 12 (Metabolism and Toxicity DIS 1)

October 23 (Thu.) 13:45-15:45 Room B (1F 2nd Exhibition Hall D)

Current understanding of gastrointestinal metabolism and disorder, and their prediction utilizing novel evaluation systems

ChairToru Usui
Sumitomo Pharma Co., Ltd.
ChairDaigo Asano
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY12-1Characterization of intestinal epithelial cells from adult stem cell-derived human intestinal organoids/spheroids and their application for pharmacokinetic evaluation
SpeakerKazuyoshi Michiba
Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Company, Limited
SY12-2Development of reproducible intestinal organoid-derived monolayer model and application to drug absorption evaluation
SpeakerKai Tanaka
Pharmaceutical Science Dept., Chugai Pharmaceutical Co., Ltd.
SY12-3Multi-faceted approaches to exploring the pathogenesis of gastrointestinal toxicity (Tentative)
SpeakerAi Okamura
Nonclinical Biomedical Science, Astellas Pharma Inc.
SY12-4Development of a Predictive Model for Gastrointestinal Toxicity Induced by Drugs Using Intestinal Crypt-Derived Cells
SpeakerYoshiki Hashimoto and Hiroyuki Kusuhara
Graduate School of Pharmaceutical Sciences, The University of Tokyo

Symposium 13 (Microphysiological system and iPS DIS)

October 23 (Thu.) 13:45-16:15 Room C (B1F 1st Exhibition Hall A)

Let’s talk honestly! ~implementation of microphysiological system into drug discovery and development~

ChairKazuhiro Tetsuka
Early Development & Translational Science, Astellas Pharma Inc.
ChairHiroyuki Mizuguchi
Graduate School of Pharmaceutical Sciences, Osaka University
SY13-1Engineering intestinal MPS for next-generation pharmaceutical research (tentative)
SpeakerKazuo Takayama
Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo
SY13-2Development of drug discovery and cardiotoxicity testing platform using iPS cell-derived 3D mature cardiac tissues
SpeakerShunsuke Funakoshi
Center for iPS Cell Research and Application, Kyoto University
Panel Discussion
SY13-3How to implement MPS into drug discovery and development? -Challenges and Opportunities-
SpeakerShinji Iwasaki
Drug Metabolism, Pharmacokinetics & Modeling, Research, Takeda Pharmaceutical Company Limited
SY13-4NAMs and MPS usage in pharmaceutical R&D: current situation and future trends
SpeakerMario Beilmann and Naoki Ishiguro
Boehringer Ingelheim Pharma GmbH & Co. KG
SY13-5Challenges and actions for implementing MPS in our R&D
SpeakerKazuhiro Tetsuka
Early Development & Translational Science, Astellas Pharma Inc.
Panel Discussion

Symposium 14 (Regulation DIS)

October 23 (Thu.) 13:45-16:15 Room D (B1F 1st Exhibition Hall B)

Practices and Perspectives on Drug-Drug Interaction Assessment After Implementation of ICH M12

ChairRyota Shigemi
Bayer Yakuhin, Ltd.
ChairNaomi Nagai
Musashino University
SY14-1Summary and review points regarding ICH M12 guideline
SpeakerMotohiro Hoshino
Pharmaceuticals and Medical Devices Agency
SY14-2HepaSH cells, a novel platform to assess the clearance of low metabolic turnover compounds and CYP induction (Tentative)
SpeakerSatoshi Tsuruta
Chugai Research Institute for Medical Science, Inc.
SY14-3Expanding the Clinical Data Set on Endogenous Biomarkers for Application in Drug Transporter-Mediated DDI Risk Assessment
SpeakerHiroyuki Kusuhara
Graduate School of Pharmaceutical Sciences, The University of Tokyo
SY14-4Drug interactions between therapeutic proteins and chemical drugs
SpeakerYoshiro Saito
National Institute of Health Sciences

Asia Joint Symposium

October 21 (Tue.) 14:15-16:45 Room C (B1F 1st Exhibition Hall A)

Shaping the Future DMPK Studies Through Asian Scientific Excellence

ChairTomomi Furihata
Laboratory of Advanced Drug Development Sciences, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
ChairHiroshi Arakawa
Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
ASY-1The development and validation of a gut-liver-on-chip model: its hepatic differentiation of liver progenitor cells and the activity of CYP450s
SpeakerHuichang Bi
School of Pharmaceutical Sciences, Southern Medical University
ASY-2Human Hepatocyte Multispheroid Array Method for the Assessment of Metabolism and Metabolic Clearance of bRo5 compounds
SpeakerVamsi Madgula
Dmpk & Toxicology Services at SAI Life Sciences Ltd
ASY-3Increase Water Solubility of Thai Herbal Extracts Could Improve Systemic Exposure of Its Bioactive Constituents and Alleviate Inflammatory Metabolomes in Dog and Human
SpeakerPhisit Khemawoot
Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand
ASY-4From Within: Harnessing Proteins’ Inherent Potential with Protein Nanocluster Technology in Cancer Therapy
SpeakerJae-Young Lee
College of Pharmacy, Seoul National University, Seoul, Republic of Korea
ASY-5Development of novel chemical entities for SARS-CoV-2 protease using structure guided approach- validation from biochemical to 3D cell based models
SpeakerAnandi Karumbati
Institute for Stem Cell Science and Regenerative Medicine
ASY-6Development of drug-induced kidney injury assay using 3D-RPTECs
SpeakerHiroshi Arakawa
Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University

The Predoctoral Researcher-Initiative Session (PRIS) 2025

October 22 (Wed.) 8:50-11:00 Room E (B1F Main Conference Room)

Corporate Rising Talents Initiative Session (CoRTIS)

October 22 (Wed.) 8:30-11:00 Room D (B1F 1st Exhibition Hall B)